Lyse may refer to:
People Lyse Doucet (born 1958), Canadian journalist, presenter and correspondent for BBC World Service radio and BBC World television Lyse Richer (born 1958), Canadian administrator and music teacher Carl L. Lyse (1899–1986), American businessman and politician
Places Lyse Abbey, a former Cistercian abbey in Norway Lyse, an alternative name of Lysebotn, Norway Łyse, Masovian Voivodeship, a village in east-central Poland Łyse, Podlaskie Voivodeship, a village in north-east Poland
Other Lyse AS, a Norwegian power and telecommunications company Lyse (mythology), daughter of Thespius and Megamede in Greek mythology, who bore Heracles a son, Eumedes Lysine exporter (LysE), a superfamily of particular transport proteins Lyse, a verb referring to the process of lysis, the death of a cell by bursting