The year 1627 in science and technology involved some significant events.
Astronomy Johannes Kepler's Rudolphine Tables are published.
Exploration January – The Dutch ship 't Gulden Zeepaert, skippered by François Thijssen, sails along the south coast of Australia.
Medicine Adriaan van den Spiegel's is published posthumously in Venice with illustrations by Giulio Casserio. Gaspare Aselli's is published posthumously in Milan.
Publications Francis Bacon's , or A Natural History and New Atlantis are published posthumously.
Births January 25 – Robert Boyle, Anglo-Irish chemist (died 1691) November 29 – John Ray, English naturalist (died 1705)
Deaths February 22 – Olivier van Noort Dutch circumnavigator (born 1558) July 20 – Guðbrandur Þorláksson, Icelandic mathematician and cartographer (born 1541) October 21 – Frederick de Houtman, Dutch explorer (born 1571)
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