Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor.
It is used for the treatment of cardiopathy and renal disorders.
Synthesis The reaction of bis(3-hydroxypropyl)ethylene diamine (1) with 1-bromo-3-chloropropane (2) gives the homopiperazine derivative 3. Esterification by reaction with 3,4,5-trimethoxybenzoyl chloride (4) completes the synthesis of dilazep (5).ThiemeGB1107470 idem Herbert Arnold, Kurt Pahls, Rolf Rebling, Norbert Brock, Hans-Dieter Lenke, (1970 to Asta Werke Ag Chem Fab)
See also Hexobendine, a drug with similar chemical structure
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