Manothrix is a genus of plants in the family Apocynaceae, first described as a genus in 1878.Miers, John. 1878. Manothrix. On the Apocynaceae of South America 28-29. Tropicos, genus Manothrix The entire genus is endemic to Brazil.

In 1993, Cecilia Carmen Xifreda published an analysis of the two species of the genus and concluded that Manothrix nodosa = Mesechites trifidus (Apocynaceae) and Manothrix valida = Hillia parasitica (Rubiaceae). Mesechites trifidus and Hillia parasitica were both described before Manothrix, so have priority as names.

SpeciesThe Plant List, genus Manothrix Manothrix nodosa Miers Manothrix valida Miers

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