Saint-Pierre, St Pierre or St. Pierre is a surname. Notable people with the surname include:
Charles-Irénée Castel de Saint-Pierre (1658–1743), proposed the creation of a European league of 18 sovereign states Georges St-Pierre (born 1981), Canadian MMA fighter Guy Saint-Pierre (1934–2022), Canadian politician and businessman Jacques-Henri Bernardin de Saint-Pierre (1737–1814), French writer and botanist Liliane Saint-Pierre (born 1948), Belgian singer Marie-Josée Saint-Pierre (born 1978), Canadian filmmaker Allen St. Pierre, executive director of the National Organization for the Reform of Marijuana Laws Annie St-Pierre, Canadian film director and producer Brian St. Pierre (born 1979), American football quarterback Christine St-Pierre (born 1953), journalist and Quebec politician Éric St-Pierre, Canadian politician Jonathan St-Pierre (born 1983), Canadian professional football player Kim St-Pierre (born 1978), Canadian ice hockey player Martin St. Pierre (racewalker) (born 1972), Canadian racewalker Martin St. Pierre (ice hockey) (born 1983), Canadian ice hockey player Monique St. Pierre (born 1953), German-American Playboy model and actress