Van Opstal is a Dutch/Flemish surname. Bearers of the name include:
Arnold Van Opstal, a Filipino-German professional basketball player Gaspar Jacob van Opstal the Younger (1654–1717), a Flemish painter Gerard van Opstal (1594 or 1597–1668), a Flemish Baroque sculptor Henri van Opstal (born 20 February 1989), a Dutch kickboxer