Thissen is a surname. Notable people with the surname include:

David Thissen (born c. 1950), American professor of psychology Frans Thissen (1909–?), Belgian rower Jean Thissen (born 1946), Belgian footballer Karin Thissen (born 1960), German politician Paul Thissen (born 1966), American politician Tof Thissen (born 1957), Dutch politician Werner Thissen (1938–2025), German Roman Catholic archbishop

See also Thiessen (disambiguation) Thijssen Thyssen (disambiguation)